Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.65 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22470032 | 0.86 | GBA1 (0.58) | GBA1LTB4RLTB4R2FUCA1SLC18A3 | |
| SCHEMBL22483044 | 0.86 | GBA1 (0.58) | GBA1LTB4RLTB4R2FUCA1SLC18A3 | |
| SCHEMBL22520561 | 0.80 | GBA1 (0.57) | GBA1LTB4RLTB4R2FUCA1SLC18A3 | |
| SCHEMBL1629688 | 0.79 | GBA1 (1.00) | GBA1PYGL | |
| SCHEMBL29016930 | 0.78 | GBA1 (0.55) | GBA1LTB4RLTB4R2SLC18A3 | |
| Hydrochloric Acid SCHEMBL1627209 | 0.77 | GBA1 (0.97) | GBA1PYGL | |
| SCHEMBL11474633 | 0.77 | GBA1 (0.53) | GBA1LTB4RLTB4R2SLC18A3 | |
| SCHEMBL22433184 | 0.76 | GBA1 (0.49) | GBA1LTB4RLTB4R2FUCA1SLC18A3 | |
| SCHEMBL19047789 | 0.76 | GBA1 (0.49) | GBA1LTB4RLTB4R2FUCA1SLC18A3 | |
| SCHEMBL19739571 | 0.76 | GBA1 (0.49) | GBA1LTB4RLTB4R2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252738-A | 1,2-Halohydrincarboxylic acid esters and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |