Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867712 | 1.00 | PTGS1 (0.57) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL11391035 | 0.93 | PTGS1 (0.54) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL8868262 | 0.92 | PTGS1 (0.59) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL11382384 | 0.92 | PTGS1 (0.59) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL8867907 | 0.89 | PTGS1 (0.51) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL8867896 | 0.88 | PTGS1 (0.54) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL11385352 | 0.88 | PTGS1 (0.65) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL8868170 | 0.88 | PTGS1 (0.65) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL11310371 | 0.87 | PTGS1 (0.60) | PTGS1ALDH1A1HSD17B10MAPTKMT2A | |
| Cefsumide SCHEMBL30688405 | 0.86 | HSD17B10 (0.75) | PTGS1ALDH1A1HSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029557-A2 | 7-Acylamino-3-substituted cephalosporanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-03 | — | — | EP | claimed |