Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.47 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dazidamine SCHEMBL286621 | 0.73 | KDM4E (0.49) | CYP1A2ADRA1AHRH3KDM4EGUCY1B2 | |
| SCHEMBL1170095 | 0.65 | SCN8A (0.50) | CYP1A2KDM4ESCN8AKMT2APTGER4 | |
| SCHEMBL1170105 | 0.65 | CYP1A2 (0.50) | CYP1A2CYP2D6SCN8AKMT2APTGER4 | |
| Benzydamine SCHEMBL29376229 | 0.64 | HRH3 (1.00) | CYP1A2ADRA1AHRH3KDM4EGUCY1B2 | |
| Benzydamine SCHEMBL26172 | 0.64 | HRH3 (1.00) | CYP1A2ADRA1AHRH3KDM4EGUCY1B2 | |
| SCHEMBL25247023 | 0.64 | SCN8A (0.49) | CYP1A2KDM4ESCN8APTGER4L3MBTL1 | |
| Benzydamine SCHEMBL8078518 | 0.63 | HRH3 (0.97) | CYP1A2ADRA1AHRH3KDM4EGUCY1B2 | |
| SCHEMBL8018576 | 0.63 | KDM4E (0.93) | CYP1A2ADRA1AHRH3KDM4EGUCY1B2 | |
| Benzydamine SCHEMBL42644 | 0.63 | POLB (1.00) | CYP1A2ADRA1AHRH3KDM4EGUCY1B2 | |
| Benzydamine SCHEMBL42645 | 0.63 | POLB (1.00) | CYP1A2ADRA1AHRH3KDM4EGUCY1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264618-A | Basic thio-indazoles | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-04-28 | — | — | US | disclosed |