Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | DRD1 | P21728 | 14/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11395200 | 0.89 | DRD1 (0.63) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| SCHEMBL11394877 | 0.89 | DRD1 (0.63) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| Hydrochloric Acid SCHEMBL11401715 | 0.88 | DRD1 (0.64) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| Hydrochloric Acid SCHEMBL11407557 | 0.88 | DRD1 (0.64) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| SCHEMBL11390914 | 0.80 | DRD1 (0.60) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| SCHEMBL11392346 | 0.79 | DRD1 (0.59) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| SCHEMBL11403973 | 0.79 | DRD1 (0.59) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| SCHEMBL16263409 | 0.79 | DRD1 (0.72) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| SCHEMBL11404972 | 0.78 | DRD1 (0.60) | CYP2D6CYP3A4DRD1HSD17B10THPO | |
| SCHEMBL11401170 | 0.78 | DRD1 (0.58) | CYP2D6CYP3A4DRD1HSD17B10THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284555-A | NEUROLEPTIC, ANTIDEPRESSANT, SEDATIVE | SCHERING CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0005299-A1 | Substituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, process for the preparation thereof, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-11-14 | — | — | EP | disclosed |