Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.47 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390428 | 0.92 | NR1I2 (0.56) | TDP1MAPTABCC4NR1I2HTR2C | |
| SCHEMBL11084504 | 0.89 | TDP1 (0.56) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11084508 | 0.89 | TDP1 (0.56) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL16976192 | 0.88 | MAPT (0.53) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11393208 | 0.88 | TDP1 (0.43) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL2588286 | 0.86 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL12567053 | 0.86 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL2594857 | 0.86 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11082764 | 0.85 | KCNH2 (0.47) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11082766 | 0.85 | KCNH2 (0.47) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025017-A1 | Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter | CIBA-GEIGY AG (CH) | 1981-03-11 | — | — | EP | disclosed |