Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392061 | 0.91 | RXFP1 (0.68) | RXFP1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL11390674 | 0.90 | RXFP1 (0.66) | RXFP1PTGESKDM4EPPARGNCOA2 | |
| SCHEMBL11396688 | 0.89 | RXFP1 (0.65) | RXFP1HDAC1HDAC2PTGESKDM4E | |
| SCHEMBL11397899 | 0.89 | RXFP1 (0.72) | RXFP1HDAC1HDAC2PTGESKDM4E | |
| SCHEMBL11392290 | 0.89 | RXFP1 (0.65) | RXFP1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL11395337 | 0.86 | RXFP1 (0.72) | RXFP1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL11387887 | 0.86 | RXFP1 (0.62) | RXFP1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL11397081 | 0.86 | RXFP1 (0.65) | RXFP1HDAC1HDAC2PTGESKDM4E | |
| SCHEMBL17318585 | 0.85 | NPC1 (0.61) | RXFP1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL11398957 | 0.83 | TP53 (0.65) | RXFP1KDM4EPPARGNCOA2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271166-A | N-(1,3,4-Thiadiazol-2-yl)benzamides | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4141984-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | disclosed |