Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 7/20 | 1.00 |
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11393042 | 0.98 | P4HTM (0.97) | P4HTMPPARASTING1CXCR1CXCR2 | |
| Acetic Acid SCHEMBL11394010 | 0.96 | P4HTM (0.92) | P4HTMPPARASTING1CXCR1CXCR2 | |
| SCHEMBL11398234 | 0.88 | P4HTM (0.78) | P4HTMALDH1A1KDM4EASPHRIOX2 | |
| SCHEMBL11387402 | 0.87 | P4HTM (0.76) | P4HTMPPARASTING1CXCR1CXCR2 | |
| SCHEMBL11392796 | 0.85 | P4HTM (0.74) | P4HTMPPARASTING1CXCR1CXCR2 | |
| SCHEMBL11387629 | 0.84 | P4HTM (0.72) | P4HTMPPARACXCR1CXCR2ALDH1A1 | |
| SCHEMBL11394043 | 0.81 | P4HTM (0.67) | P4HTMPPARASTING1CXCR1CXCR2 | |
| SCHEMBL754198 | 0.78 | P4HTM (0.63) | P4HTMLMNAALDH1A1KDM4E | |
| SCHEMBL1663181 | 0.78 | PPARA (0.64) | P4HTMPPARASTING1ALDH1A1KDM4E | |
| SCHEMBL26049197 | 0.77 | P4HTM (0.62) | P4HTMALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273779-A | Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids | CIBA-GEIGY CORPORATION (US) | 1981-06-16 | — | — | US | claimed |
| US-4273779-A | Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids | CIBA-GEIGY CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |