Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CLPP | Q16740 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10795625 | 0.99 | TSHR (0.54) | TSHRHTTCLPPGAAGFER | |
| SCHEMBL10795549 | 0.88 | TSHR (0.54) | TSHRHTTCLPPGAAGFER | |
| SCHEMBL10796025 | 0.87 | TSHR (0.51) | TSHRHTTCLPPGAAGFER | |
| SCHEMBL11060686 | 0.85 | TSHR (0.51) | TSHRHTTCLPPGAAGFER | |
| SCHEMBL10798553 | 0.83 | TSHR (0.56) | TSHRHTTCLPPGAAGFER | |
| SCHEMBL10800864 | 0.82 | TSHR (0.50) | TSHRHTTCLPPGAAGFER | |
| SCHEMBL10796109 | 0.82 | TSHR (0.48) | TSHRHTTCLPPGAAGFER | |
| SCHEMBL11067509 | 0.78 | TSHR (0.50) | TSHRHTTCLPPGAAGFER | |
| Hydrochloric Acid SCHEMBL10795579 | 0.77 | TSHR (0.49) | TSHRHTTCLPPGAAGFER | |
| SCHEMBL10798400 | 0.76 | TSHR (0.55) | TSHRHTTCLPPGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298734-A | PHOSPHODIESTERASE INHIBITORS, BRONCHODILATORS, PERIPHERAL VASODILATORS | MEAD JOHNSON & COMPANY (US) | 1981-11-03 | — | — | US | disclosed |