Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.75 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.72 |
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222245 | 0.86 | HCAR2 (1.00) | HCAR2HCAR3GPR84 | |
| SCHEMBL11403580 | 0.86 | HCAR2 (1.00) | HCAR2HCAR3GPR84 | |
| SCHEMBL11408463 | 0.86 | HCAR2 (1.00) | HCAR2HCAR3GPR84 | |
| SCHEMBL11231985 | 0.86 | HCAR2 (1.00) | HCAR2HCAR3GPR84 | |
| SCHEMBL11412506 | 0.86 | HCAR2 (1.00) | HCAR2HCAR3GPR84 | |
| SCHEMBL11226614 | 0.86 | HCAR2 (1.00) | HCAR2HCAR3GPR84 | |
| Hydrochloric Acid SCHEMBL11397237 | 0.84 | HCAR2 (0.97) | HCAR2HCAR3GPR84 | |
| SCHEMBL7172516 | 0.84 | HCAR2 (1.00) | HCAR2HCAR3RIPK1 | |
| SCHEMBL15964804 | 0.83 | HCAR2 (0.74) | HCAR2HCAR3GPR84RIPK1KDM5A | |
| SCHEMBL11365652 | 0.81 | HCAR2 (0.69) | HCAR2HCAR3GPR84RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029363-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |