Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907531 | 0.87 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| Chloromethane SCHEMBL27654435 | 0.87 | TSHR (0.52) | KCNN4CES2MGLLTSHRMAPK1 | |
| SCHEMBL29635721 | 0.87 | TSHR (0.56) | KCNN4CES2MGLLTSHRMAPK1 | |
| SCHEMBL168760 | 0.87 | TSHR (0.56) | KCNN4CES2MGLLTSHRMAPK1 | |
| Formaldehyde SCHEMBL28200835 | 0.85 | KCNN4 (0.52) | PTPN1CA1CA2MMP1MMP2 | |
| Water SCHEMBL28262645 | 0.85 | TSHR (0.54) | KCNN4CES2MGLLTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL28030628 | 0.85 | TSHR (0.54) | KCNN4CES2MGLLTSHRMAPK1 | |
| SCHEMBL28476434 | 0.85 | CA1 (0.53) | PTPN1CA1CA2MMP1MMP2 | |
| SCHEMBL27497591 | 0.84 | KCNN4 (0.47) | PTPN1KCNN4CES2MGLLTSHR | |
| Bromomethane SCHEMBL27825377 | 0.81 | TSHR (0.50) | KCNN4CES2MGLLTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961662-A | Preparation method of 2-fluoro-6-trifluoromethyl benzenesulfonyl chloride | HUNAN RES INST OF CHEMICAL INDUSTRY CO LTD | 2015-10-07 | — | — | CN | claimed |
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | claimed |
| CN-104341326-A | Preparation method for 2-substituted 6-(trifluoromethyl)benzenesulphonyl chloride | TIANJIN NUOWEIKANG BIOTECHNOLOGY CO LTD | 2015-02-11 | — | — | CN | claimed |
| CN-115703728-A | Trifluoromethyl phenyl thiocyanate compound | 上海泰初化工技术有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-110317137-A | 9,10- anthraquinone analog compound or its pharmaceutically acceptable salt and its medicinal usage | 复旦大学 | 2019-10-11 | — | — | CN | disclosed |
| CN-108698982-A | FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF | 日产化学工业株式会社 | 2018-10-23 | — | — | CN | disclosed |
| CN-105175284-B | Amides compound, preparation method and its medical usage | 中国药科大学 | 2017-06-16 | — | — | CN | disclosed |
| CN-104693080-B | A kind of 6-replaces the preparation method of-2-trifluoromethyl benzene sulfonyl chloride | 南京正荣医药化学有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-103739525-B | A kind of preparation method of substituted phenylsulfonyl chloride | JINGBO AGROCHEMICALS TECHNOLOGY Co.,Ltd. (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-103694170-B | The fluoro-1-methyl isophthalic acid of 6,7-bis-, the synthetic method of 2,3,4-four hydrogen isoquinoline hydrochloric acid salt | CHANGZHOU XIAQING CHEMICAL CO., LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-105431421-A | Heterocyclic compounds as hedgehog signaling pathway inhibitors | REDX PHARMA LTD | 2016-03-23 | — | — | CN | disclosed |
| EP-1786811-A2 | TRIAZOLOPYRIDINE COMPOUNDS | Pharmacia & Upjohn Company LLC (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-1781655-A2 | TRIAZOLOPYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATION | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006029210-A2 | ACYCLIC 1,3-DIAMINES AND USES THEREFOR | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006018735-A2 | TRIAZOLOPYRIDINE COMPOUNDS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |
| WO-2006018727-A2 | TRIAZOLOPYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |
| CN-1617855-A | Cytosolic phospholipase A2Inhibitors | WYETH CORP (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1471532-A | Process for the preparation of z-alkoxy-6-trifluoromethyl-N-[(C1,2,4] triazolo[1,5-C] pyrimidin-2-yl) benzensulfonamides | �ݶ�ũ������˾ | 2004-01-28 | — | — | CN | disclosed |
| CN-1165144-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| CN-1165143-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |