Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 3/20 | 0.75 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.75 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.67 |
| ▸ | CRYAB | P02511 | 1/20 | 0.62 |
| ▸ | HMGCR | P04035 | 1/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.62 |
| ▸ | ITGAV | P06756 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.62 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.62 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.62 |
| ▸ | GPR183 | P32249 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399025 | 1.00 | OSBP (0.75) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL25338196 | 1.00 | OSBP (0.75) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL25339557 | 1.00 | OSBP (0.75) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL12526779 | 0.94 | GPBAR1 (0.69) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL5341062 | 0.87 | GPBAR1 (0.72) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL21000302 | 0.87 | GPBAR1 (0.72) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL20972927 | 0.87 | GPBAR1 (0.72) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL20972926 | 0.87 | GPBAR1 (0.72) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL14490144 | 0.87 | GPBAR1 (0.72) | OSBPOSBP2GPBAR1MAPTTHRB | |
| SCHEMBL22472242 | 0.87 | GPBAR1 (0.72) | OSBPOSBP2GPBAR1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55066600-A | — | — | None | — | — | JP | disclosed |
| JP-S5566600-A | PREPARATION OF 3BETA,25-DEHYDROXY-5ALPHA-CHOLEST-5-ENE OR ITS 3BETA- ACETATE | TEIJIN LTD | 1980-05-20 | — | — | JP | disclosed |