Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30683723 | 0.80 | ERN1 (0.48) | ERN1MAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL12767273 | 0.77 | ERN1 (1.00) | ERN1GAACYP2D6MAPTALDH1A1 | |
| SCHEMBL12470882 | 0.77 | ERN1 (0.68) | ERN1CYP3A4CYP2D6MAPTALDH1A1 | |
| SCHEMBL12767262 | 0.75 | ERN1 (0.60) | ERN1KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL12470883 | 0.75 | MEN1 (0.55) | ERN1KDM4ECYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31529056 | 0.73 | TSHR (0.57) | ERN1CYP3A4GAAMAPTALDH1A1 | |
| SCHEMBL31529055 | 0.73 | TSHR (0.57) | ERN1CYP3A4GAAMAPTALDH1A1 | |
| SCHEMBL2082412 | 0.73 | TSHR (0.57) | ERN1CYP3A4GAAMAPTALDH1A1 | |
| SCHEMBL8951248 | 0.73 | MAPT (0.44) | ERN1GAACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2084236 | 0.71 | GFER (0.56) | ERN1KDM4EMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4291032-A | ANALGESICS | RHONE POULENC INDUSTRIES (FR) | 1981-09-22 | — | — | US | disclosed |