SCHEMBL11399404

SCHEMBL11399404

CCCC[Si]1(Cl)CCCC1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11397904 0.97 CYP1A2 (0.31)
SCHEMBL11395211 0.97 CYP1A2 (0.31)
SCHEMBL10964552 0.97 CYP1A2 (0.31)
SCHEMBL8018691 0.90 TSHR (0.32) TSHR
SCHEMBL11396924 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL11397985 0.88 TSHR (0.36) TSHR
SCHEMBL6470505 0.87 TSHR (0.33) TSHR
SCHEMBL29599822 0.85
SCHEMBL29599839 0.82
SCHEMBL27971882 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4296240-A ANTI-ATHEROSCLEROTIC AGENTS SANDOZ, INC. (US) 1981-10-20 US disclosed