Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264951 | 0.77 | HSD17B10 (0.39) | HPGDTSHRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11273592 | 0.73 | KDM4E (0.52) | HPGDALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL11397116 | 0.68 | HPGD (0.58) | HPGDALDH1A1HSD17B10HTR4 | |
| SCHEMBL14430683 | 0.68 | NPSR1 (0.53) | HPGDL3MBTL1TSHRALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11263860 | 0.68 | HPGD (0.57) | HPGDALDH1A1HSD17B10HTR4 | |
| SCHEMBL14430706 | 0.67 | NAMPT (0.67) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14430680 | 0.66 | SMYD2 (0.60) | HPGDL3MBTL1KDM4EKMT2A | |
| SCHEMBL8761519 | 0.66 | SMN1; SMN2 (0.52) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2ACHE | |
| SCHEMBL13453975 | 0.66 | SMN1; SMN2 (0.52) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2ACHE | |
| SCHEMBL5473935 | 0.65 | HPGD (0.66) | HPGDL3MBTL1TSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255580-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | SIOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-03-10 | — | — | US | claimed |