Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12470883 | 0.81 | MEN1 (0.55) | ERN1MAPTMAOATDP1ALDH1A1 | |
| SCHEMBL11400118 | 0.80 | MAPT (0.56) | ERN1KDM1AMAPTMAOATDP1 | |
| SCHEMBL11401198 | 0.77 | ERN1 (0.43) | ERN1KDM1AMAPTTDP1ALDH1A1 | |
| SCHEMBL11402286 | 0.77 | HTR2C (0.43) | ERN1KDM1AMAPTTDP1ALDH1A1 | |
| SCHEMBL2084131 | 0.74 | MAPT (0.66) | ERN1KDM1AMAPTMAOATDP1 | |
| SCHEMBL12264767 | 0.74 | TSHR (0.50) | ERN1MAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL2082412 | 0.73 | TSHR (0.57) | ERN1MAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL31529055 | 0.73 | TSHR (0.57) | ERN1MAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL31529056 | 0.73 | TSHR (0.57) | ERN1MAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL8951248 | 0.73 | MAPT (0.44) | ERN1MAPTTDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4291032-A | ANALGESICS | RHONE POULENC INDUSTRIES (FR) | 1981-09-22 | — | — | US | disclosed |