Licoagrochacone A

Licoagrochacone A

SCHEMBL114042

C=CC(C)(C)c1cc(/C=C/C(=O)c2ccc(O)cc2)c(OC)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 13/20 1.00
DPP4 P27487 4/20 1.00
ABCG2 Q9UNQ0 2/20 1.00
IDH1 O75874 1/20 1.00
ABCB1 P08183 1/20 1.00
UGT1A1 P22309 1/20 1.00
ABCC1 P33527 1/20 1.00
PRMT6 Q96LA8 1/20 1.00
CAPN1 P07384 1/20 0.60
CTSL P07711 1/20 0.60
CTSB P07858 1/20 0.60
TDP1 Q9NUW8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Licoagrochacone A SCHEMBL30383634 1.00 PTPN1 (1.00) PTPN1DPP4ABCG2IDH1ABCB1
Licoagrochacone A SCHEMBL29929441 1.00 PTPN1 (1.00) PTPN1DPP4ABCG2IDH1ABCB1
Licoagrochacone A SCHEMBL4906294 1.00 PTPN1 (1.00) PTPN1DPP4ABCG2IDH1ABCB1
SCHEMBL24026322 0.92 PTPN1 (0.85) PTPN1DPP4ABCG2IDH1ABCB1
SCHEMBL7191524 0.92 PTPN1 (1.00) PTPN1DPP4ABCG2IDH1ABCB1
SCHEMBL7191527 0.92 PTPN1 (1.00) PTPN1DPP4ABCG2IDH1ABCB1
Licoagrochacone A SCHEMBL25196053 0.89 PTPN1 (0.80) PTPN1DPP4ABCG2IDH1ABCB1
SCHEMBL7187524 0.88 PTPN1 (0.79) PTPN1DPP4ABCG2IDH1ABCB1
SCHEMBL7187519 0.88 PTPN1 (0.79) PTPN1DPP4ABCG2IDH1ABCB1
SCHEMBL7178841 0.88 PTPN1 (0.78) PTPN1DPP4ABCG2IDH1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3432 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115252599-B Application of licochalcone A and composition of glabridin and licochalcone A in preparation of medicines for treating colorectal cancer 宁夏医科大学 2026-05-19 CN claimed
CN-122067647-A Prediction and depth verification integration method for traditional Chinese medicine compound action mechanism research 国药集团德众(佛山)药业有限公司 2026-05-19 CN claimed
CN-122036553-A Compound, nanoparticle, composition and application thereof 北京大学第三医院(北京大学第三临床医学院) 2026-05-15 CN claimed
CN-122005513-A Anti-tumor and/or anti-iron death small molecule composition and application thereof 北京慧宝源生物技术股份有限公司 2026-05-12 CN claimed
WO-2026087103-A1 COMBINATION OF RETINOL, ALKYLAMIDOTHIAZOLES AND FLAVONOIDS FOR IMPROVING ACTIVE SUBSTANCE STABILIZATION BEIERSDORF AG (DE) 2026-04-30 WO claimed
EP-4713433-A2 LIVER ORGANOIDS WITH INTRAHEPATIC SYMPATHETIC NERVES, AND METHODS OF USE THEREOF Children's Hospital Medical Center (US) 2026-03-25 EP claimed
US-20260061019-A1 Topical Compositions For Regulating Sebum Production ELC MAN LLC (US) 2026-03-05 US claimed
EP-4157208-B1 MINERAL-OIL-FREE W/O EMULSION WITH A VARIABLE CONSISTENCY BEIERSDORF AG (DE) 2026-03-04 EP claimed
EP-4701742-A1 RETINOL-CONTAINING COSMETIC PREPARATION WITH GOOD SKIN COMPATIBILITY Beiersdorf AG (DE) 2026-03-04 EP claimed
EP-4701743-A1 RETINOL-CONTAINING COSMETIC PREPARATION WITH GOOD STABILITY, SKIN COMPATIBILITY AND EFFECTIVENESS Beiersdorf AG (DE) 2026-03-04 EP claimed
CN-1520811-A External composition containing oil-soluble licorice extract and method for stabilizing the same 丸善制药株式会社 2004-08-18 CN claimed
EP-1440688-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGANDS AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2004-07-28 EP claimed
US-20030199581-A1 Boswellin compositions enhanced with 3-beta-acetyl-11-keto-beta-boswellic acid (\"AKBA\") industrial manufacture and uses BIOPHYSICA, INC. 2003-10-23 US claimed
WO-2003077860-A2 BOSWELLIN COMPOSITIONS ENHANCED WITH 3-β-ACETYL-11-KETO-β-BOSWELLIC ACID (“AKBA”), INDUSTRIAL MANUFACTURE AND THEIR USES BIOPHYSICA, INC. (US) 2003-09-25 WO claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-6603046-B1 The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. LICA PHARMACEUTICALS A/S (DK) 2003-08-05 US claimed
US-6486203-B1 Treating inflammatory diseases of the head and neck with cyclooxygenase-2 inhibitors CORNELL RESEARCH FOUNDATION, INC. 2002-11-26 US claimed
EP-0634927-B1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA LICA PHARMACEUTICALS AS (DK) 2001-07-04 EP claimed
WO-1995006628-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-03-09 WO claimed
CN-1095590-A By parasite or bacterial treatment of diseases and prevention STATENS SERUMINSTITUT (DK) 1994-11-30 CN claimed