SCHEMBL11409134

SCHEMBL11409134

CCCCC1CCC(C2CCC(C(=O)Oc3ccc(C)cc3)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
F2 P00734 1/20 0.43
ELANE P08246 1/20 0.42
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11407692 0.96 HTT (0.44) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL14401435 0.96 HTT (0.49) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL11404057 0.95 HTT (0.43) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL11418390 0.95 HTT (0.43) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL11406438 0.95 HTT (0.43) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL8217386 0.92 HTT (0.47) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL11406065 0.92 KMT2A (0.47) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL11405326 0.90 KMT2A (0.45) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL11413156 0.90 KMT2A (0.45) KMT2AHTTSMN1; SMN2TDP1GAA
SCHEMBL11416135 0.90 SMN1; SMN2 (0.45) KMT2AHTTSMN1; SMN2TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9222023-B2 Liquid crystal composition and display device thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2015-12-29 US disclosed
US-20150076405-A1 LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2015-03-19 US disclosed
US-4229315-A FOR DISPLAY ELEMENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-10-21 US disclosed