Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.69 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365652 | 1.00 | HCAR2 (0.69) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL11400467 | 1.00 | HCAR2 (0.69) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL11241327 | 1.00 | HCAR2 (0.69) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL11231576 | 1.00 | HCAR2 (0.69) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL11220652 | 1.00 | HCAR2 (0.69) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL9367631 | 0.99 | HCAR2 (0.68) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL6366232 | 0.94 | HCAR2 (0.68) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL1259028 | 0.88 | HCAR2 (0.66) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL5724811 | 0.87 | HCAR2 (0.54) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 | |
| SCHEMBL1149593 | 0.83 | HCAR2 (0.50) | HCAR2HCAR3KMT2ANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029363-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |