Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | ACR | P10323 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416378 | 1.00 | PRSS1 (0.41) | PRSS1ACRCYP2C9KMT2AMEN1 | |
| SCHEMBL11403234 | 0.91 | CYP2C9 (0.41) | CYP2C9KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11416506 | 0.91 | CYP2C9 (0.41) | PRSS1CYP2C9KMT2AMEN1MAPT | |
| SCHEMBL11403411 | 0.91 | MAPT (0.48) | PRSS1ACRCYP2C9KMT2AMAPT | |
| SCHEMBL11407641 | 0.91 | CYP2C9 (0.41) | PRSS1CYP2C9KMT2AMEN1MAPT | |
| SCHEMBL11411675 | 0.90 | ESR1 (0.44) | PRSS1ACRCYP2C9KMT2AMEN1 | |
| SCHEMBL11411005 | 0.90 | KMT2A (0.46) | CYP2C9KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11411644 | 0.88 | MAPT (0.41) | PRSS1ACRCYP2C9KMT2AMAPT | |
| SCHEMBL11408537 | 0.88 | CYP2C9 (0.41) | PRSS1ACRCYP2C9KMT2AMEN1 | |
| SCHEMBL11416289 | 0.88 | PRSS1 (0.47) | PRSS1ACRCYP2C9KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229315-A | FOR DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-10-21 | — | — | US | disclosed |