Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854916 | 0.86 | SMN1; SMN2 (0.63) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL1066335 | 0.84 | SMN1; SMN2 (0.61) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL2818579 | 0.81 | SMN1; SMN2 (0.68) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL12254507 | 0.81 | KMT2A (0.51) | KMT2ASMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL22804018 | 0.81 | KMT2A (0.51) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL29574935 | 0.80 | SMN1; SMN2 (0.71) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL8208243 | 0.80 | SMN1; SMN2 (0.66) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL4526885 | 0.80 | SMN1; SMN2 (0.66) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL8209122 | 0.80 | TDP1 (0.66) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL19876826 | 0.80 | TDP1 (0.71) | KMT2ACYP1A2CYP3A4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216226-A | GLYCINE DERIVATIVE | MEIJI SEIKA KAISHA, LTD. (JP) | 1980-08-05 | — | — | US | disclosed |