Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408186 | 1.00 | SPHK1 (0.45) | SPHK1MAPTSMN1; SMN2CYP2C9SPHK2 | |
| SCHEMBL11416206 | 0.97 | SPHK1 (0.50) | SPHK1MAPTSMN1; SMN2SPHK2THRB | |
| SCHEMBL11413919 | 0.97 | SPHK1 (0.50) | SPHK1MAPTSMN1; SMN2SPHK2THRB | |
| SCHEMBL11411622 | 0.95 | SPHK1 (0.52) | SPHK1MAPTSMN1; SMN2SPHK2THRB | |
| SCHEMBL11411631 | 0.95 | SPHK1 (0.52) | SPHK1MAPTSMN1; SMN2SPHK2THRB | |
| SCHEMBL11419283 | 0.95 | SPHK1 (0.52) | SPHK1MAPTSMN1; SMN2SPHK2THRB | |
| SCHEMBL11411012 | 0.95 | SPHK1 (0.52) | SPHK1MAPTSMN1; SMN2SPHK2THRB | |
| SCHEMBL11410617 | 0.95 | SPHK1 (0.52) | SPHK1MAPTSMN1; SMN2SPHK2THRB | |
| SCHEMBL11411710 | 0.93 | CYP2C9 (0.46) | SPHK1MAPTSMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL11412000 | 0.93 | CYP2C9 (0.46) | SPHK1MAPTSMN1; SMN2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229315-A | FOR DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-10-21 | — | — | US | disclosed |