Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633211 | 0.93 | NR1I2 (0.53) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11416757 | 0.93 | TDP1 (0.43) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11424278 | 0.92 | NR1I2 (0.42) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11411573 | 0.92 | NR1I2 (0.46) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL9599908 | 0.90 | NR1I2 (0.45) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11419994 | 0.90 | NR1I2 (0.44) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11308934 | 0.86 | NR1I2 (0.51) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11177483 | 0.85 | NR1I2 (0.46) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11419978 | 0.84 | NR1I2 (0.49) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11420021 | 0.84 | NR1I2 (0.44) | NR1I2PGRTDP1MAPTABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200745-A | 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins | ELI LILLY AND COMPANY (US) | 1980-04-29 | — | — | US | disclosed |