Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MPI | P34949 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413244 | 1.00 | MAOB (0.66) | MAOBSIRT2POLBEIF4HMAPT | |
| SCHEMBL11410155 | 0.86 | MAOB (0.59) | MAOBSIRT2POLBEIF4HMAPT | |
| SCHEMBL11410159 | 0.86 | MAOB (0.59) | MAOBSIRT2POLBEIF4HMAPT | |
| SCHEMBL11408234 | 0.85 | SIRT2 (0.71) | MAOBSIRT2POLBMAPTKDM4E | |
| SCHEMBL11408236 | 0.85 | SIRT2 (0.71) | MAOBSIRT2POLBMAPTKDM4E | |
| SCHEMBL11420954 | 0.79 | KDM4E (0.58) | MAOBSIRT2POLBEIF4HMAPT | |
| SCHEMBL11420962 | 0.79 | KDM4E (0.58) | MAOBSIRT2POLBEIF4HMAPT | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL29424118 | 0.78 | SIRT2 (0.88) | MAOBSIRT2MAPTKDM4EKMT2A | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL347862 | 0.78 | SIRT2 (0.88) | MAOBSIRT2MAPTKDM4EKMT2A | |
| SCHEMBL16323813 | 0.78 | SIRT2 (0.61) | MAOBSIRT2MAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |