SCHEMBL11414519

SCHEMBL11414519

COc1ccc(C(N)=O)cc1N=Nc1ccc(O)c(C=O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ERN1 O75460 9/20 0.52
▸ MAPT P10636 4/20 0.48
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ L3MBTL1 Q9Y468 3/20 0.48
▸ NPC1 O15118 3/20 0.48
▸ POLB P06746 3/20 0.48
▸ RAB9A P51151 3/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ PLCG1 P19174 2/20 0.48
▸ GAA P10253 2/20 0.48
▸ NPSR1 Q6W5P4 2/20 0.48
▸ THRB P10828 2/20 0.48
▸ LMNA P02545 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ CA1 P00915 3/20 0.44
▸ CA2 P00918 3/20 0.44
▸ PTGS1 P23219 1/20 0.41
▸ PTGS2 P35354 1/20 0.41
▸ MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10731975 0.80 MEN1 (0.65) ERN1MAPTMEN1KMT2AL3MBTL1
SCHEMBL11057274 0.79 PLCG1 (0.55) ERN1MAPTMEN1KMT2AL3MBTL1
SCHEMBL28564378 0.77 MAPT (0.49) MAPTMEN1KMT2AL3MBTL1NPC1
SCHEMBL28564379 0.77 MAPT (0.49) MAPTMEN1KMT2AL3MBTL1NPC1
SCHEMBL10343736 0.77 KMT2A (0.61) ERN1MAPTMEN1KMT2AL3MBTL1
SCHEMBL11647971 0.76 PLCG1 (0.52) ERN1MAPTMEN1KMT2AL3MBTL1
SCHEMBL25267061 0.75 ERN1 (0.52) ERN1MAPTMEN1KMT2AL3MBTL1
SCHEMBL25214878 0.75 ERN1 (0.52) ERN1MAPTMEN1KMT2AL3MBTL1
SCHEMBL1351199 0.74 ERN1 (0.58) ERN1L3MBTL1RAB9AALDH1A1LMNA
SCHEMBL29956840 0.73 ERN1 (0.74) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4237293-A COLORFAST SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 — — US disclosed
US-4237292-A SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 — — US disclosed
US-4237286-A COLORING PLASTICS AND LACQUERS IN YELLOW TO RED SHADES CIBA-GEIGY CORPORATION (US) 1980-12-02 — — US disclosed
US-4144258-A ORGANIC PIGMENTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1979-03-13 — — US disclosed
US-4132708-A Metal complexes of azomethines and process for their manufacture CIBA-GEIGY CORPORATION (US) 1979-01-02 — — US disclosed
US-4111947-A DYES, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1978-09-05 — — US disclosed
US-4065481-A 1:1-Azomethine-metal-complex dyestuffs CIBA-GEIGY CORPORATION (US) 1977-12-27 — — US disclosed
US-4024132-A Azomethine pigments CIBA-GEIGY CORPORATION (US) 1977-05-17 — — US disclosed
US-4022770-A COLORING CIBA-GEIGY CORPORATION (US) 1977-05-10 — — US disclosed
US-4016157-A COLORING PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1977-04-05 — — US disclosed
US-3988323-A PIGMENTS CIBA-GEIGY CORPORATION (US) 1976-10-26 — — US disclosed
US-3974149-A TONERS CIBA-GEIGY CORPORATION (US) 1976-08-10 — — US disclosed
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