Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772237 | 0.79 | TSHR (0.42) | TSHRPOLBALDH1A1LMNATP53 | |
| SCHEMBL10831649 | 0.79 | TSHR (0.46) | TSHRPOLBALDH1A1LMNATP53 | |
| SCHEMBL11774739 | 0.78 | TSHR (0.43) | TSHRPOLBALDH1A1LMNATP53 | |
| SCHEMBL11430413 | 0.77 | PPARD (0.39) | TSHRPOLBALDH1A1LMNATP53 | |
| SCHEMBL3822346 | 0.75 | POLB (0.48) | TSHRPOLBTP53TDP1GAA | |
| SCHEMBL11947800 | 0.74 | TSHR (0.40) | TSHRPOLBALDH1A1LMNATP53 | |
| SCHEMBL13779263 | 0.74 | TSHR (0.40) | TSHRPOLBALDH1A1LMNATP53 | |
| SCHEMBL10201143 | 0.74 | TSHR (0.50) | TSHRPOLBTP53TDP1GAA | |
| SCHEMBL1711012 | 0.74 | TSHR (0.50) | TSHRPOLBALDH1A1LMNATP53 | |
| SCHEMBL10719703 | 0.73 | POLB (0.33) | TSHRPOLBALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1083842-C | [1,2,4] triazolo [4,3-1] quinoxalinone derivatives, their preparation and use | NOVO NORDISK AS (DK) | 2002-05-01 | — | — | CN | disclosed |
| CN-1193974-A | [1,2,4] triazolo [4,3-1] quinoxalinone derivatives, their preparation and use | NOVO NORDISK AS (DK) | 1998-09-23 | — | — | CN | disclosed |
| US-4198354-A | Manufacture of α-formylethanephosphonic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4190650-A | Phosphonyl vinyl phosphorus compounds as pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |