Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422565 | 0.88 | TDP1 (0.58) | MAPTTDP1L3MBTL1NSD2ALDH1A1 | |
| SCHEMBL547614 | 0.84 | MAPT (0.57) | MAPTTDP1L3MBTL1NSD2ALDH1A1 | |
| SCHEMBL11425642 | 0.83 | MAPT (0.73) | MAPTTDP1L3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL9338150 | 0.82 | MAPT (0.68) | MAPTTDP1L3MBTL1NSD2ALDH1A1 | |
| SCHEMBL11417551 | 0.78 | PRSS1 (0.51) | MAPTTDP1L3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL2035745 | 0.77 | NSD2 (0.74) | MAPTTDP1L3MBTL1NSD2ALDH1A1 | |
| SCHEMBL11430442 | 0.76 | TDP1 (0.49) | MAPTTDP1L3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL1786807 | 0.76 | MAPT (0.69) | MAPTTDP1L3MBTL1NSD2ALDH1A1 | |
| SCHEMBL547801 | 0.75 | MAPT (0.58) | MAPTTDP1L3MBTL1NSD2ALDH1A1 | |
| SCHEMBL678424 | 0.73 | MAPT (0.70) | MAPTTDP1L3MBTL1NSD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202833-A | INTERMEDIATES TO BISPHENOL CARBONATES | THE UPJOHN COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
| US-4200763-A | CHEMICAL INTERMEDIATE | THE UPJOHN COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
| US-4164510-A | METAL PHTHALOCYANINE, TERT-ALKYL PEROXIDE AS CATALYST | THE UPJOHN COMPANY (US) | 1979-08-14 | — | — | US | disclosed |