Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13591418 | 0.87 | CA1 (0.40) | CA1CA9CYP1A2 | |
| SCHEMBL4477475 | 0.79 | — | — | |
| SCHEMBL6467930 | 0.75 | CA1 (0.48) | CA1CA9CYP1A2 | |
| SCHEMBL564510 | 0.75 | CA1 (0.48) | CA1CA9CYP1A2 | |
| SCHEMBL564140 | 0.70 | CA1 (0.44) | CA1CA9CYP1A2 | |
| SCHEMBL6756772 | 0.70 | CA1 (0.44) | CA1CA9CYP1A2 | |
| SCHEMBL31232833 | 0.69 | SMN1; SMN2 (0.42) | CA1CA9 | |
| SCHEMBL10954745 | 0.69 | CA1 (0.42) | CA1CA9CYP1A2 | |
| SCHEMBL10583357 | 0.67 | — | — | |
| SCHEMBL2601760 | 0.67 | SMN1; SMN2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236971-B2 | Polycyclic ester containing cyano group and lactone skeleton | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110028743-A1 | POLYCYCLIC ESTER CONTAINING CYANO GROUP AND LACTONE SKELETON | INOUE KEIZO | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028743-A1 | POLYCYCLIC ESTER CONTAINING CYANO GROUP AND LACTONE SKELETON | LSS, COASY, CYP8B1 | CA1 373/4885CA9 323/4885CYP1A2 604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.