Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionamide SCHEMBL11420245 | 1.00 | TDP1 (0.47) | TDP1ALDH1A1FFAR3ALOX15LMNA | |
| Propionamide SCHEMBL27662186 | 0.96 | TDP1 (0.50) | TDP1ALDH1A1FFAR3ALOX15LMNA | |
| Propionamide SCHEMBL6361 | 0.96 | — | — | |
| Propionamide SCHEMBL3712584 | 0.92 | — | — | |
| Propionamide SCHEMBL4727846 | 0.92 | — | — | |
| Propionamide SCHEMBL25289008 | 0.92 | — | — | |
| Propionamide SCHEMBL18282467 | 0.92 | TDP1 (0.47) | TDP1ALDH1A1FFAR3ALOX15LMNA | |
| Propionamide SCHEMBL1538372 | 0.92 | — | — | |
| Propionamide SCHEMBL7893429 | 0.92 | — | — | |
| Propionamide SCHEMBL3950633 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234501-A | Process for the preparation of organotin compounds | AKZO N.V. (NL) | 1980-11-18 | — | — | US | disclosed |