Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819605 | 0.77 | NPC1 (0.49) | POLBNPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29183778 | 0.77 | POLB (0.52) | POLBNPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11620715 | 0.74 | POLB (0.59) | POLBNPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11419205 | 0.74 | CYP2C9 (0.49) | NPC1CYP2C9ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22722990 | 0.72 | CYP2C9 (0.96) | POLBNPC1CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL22722991 | 0.72 | CYP2C9 (0.96) | POLBNPC1CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL22722997 | 0.72 | CYP2C9 (0.96) | POLBNPC1CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL11739975 | 0.71 | NPC1 (0.62) | POLBNPC1CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL1310721 | 0.71 | PTPN1 (0.55) | POLBNPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11354983 | 0.70 | GSK3B (0.64) | POLBNPC1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208335-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4143154-A | ANTI-MICROBIAL 2-NITRO-3-PHENYL BENZOFURANS SUBSTITUTED BY CARBOXY CONTAINING GROUP | RIKER LABORATORIES, INC. (US) | 1979-03-06 | — | — | US | disclosed |