Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499711 | 0.79 | NPSR1 (0.33) | KDM4E | |
| SCHEMBL11424235 | 0.68 | KDM4E (0.31) | KDM4EPKMHCAR2 | |
| SCHEMBL20031230 | 0.65 | NOTUM (0.30) | — | |
| SCHEMBL11419666 | 0.63 | — | — | |
| SCHEMBL1311693 | 0.63 | — | — | |
| SCHEMBL14472921 | 0.60 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL27682010 | 0.57 | — | — | |
| SCHEMBL31367006 | 0.56 | KDM4E (0.31) | KDM4EPKMHCAR2 | |
| Terephthalic Acid SCHEMBL31728631 | 0.47 | TSHR (0.67) | — | |
| SCHEMBL30770833 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55022648-A | — | — | None | — | — | JP | disclosed |
| US-4282235-A | Derivatives of thiazolidinecarboxylic acids and related acids | E. R. SQUIBB & SONS, INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4237134-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4237129-A | Derivatives of thiazolidinecarboxylic acids and related acids | E. R. SQUIBB & SONS, INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4192878-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-03-11 | — | — | US | disclosed |
| JP-S5522648-A | PREPARATIN OF 5-METHYL-1,4-THIAZAN-3-CARBOXYLIC ACID | TANABE SEIYAKU CO LTD | 1980-02-18 | — | — | JP | disclosed |