Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427712 | 1.00 | AKR1C3 (0.47) | AKR1C3RECQLMEN1KMT2AABCG2 | |
| SCHEMBL30937972 | 0.87 | AKR1C3 (0.55) | AKR1C3RECQLMEN1KMT2AABCG2 | |
| SCHEMBL18338901 | 0.86 | ABCG2 (0.48) | AKR1C3RECQLMEN1KMT2AABCG2 | |
| SCHEMBL1397476 | 0.85 | ABCG2 (0.53) | AKR1C3RECQLMEN1KMT2AABCG2 | |
| SCHEMBL28732347 | 0.85 | ABCG2 (0.53) | AKR1C3RECQLMEN1KMT2AABCG2 | |
| SCHEMBL3619315 | 0.84 | AKR1C3 (0.57) | AKR1C3RECQLMEN1KMT2AABCG2 | |
| SCHEMBL3881261 | 0.84 | AKR1C3 (0.57) | AKR1C3RECQLMEN1KMT2AABCG2 | |
| SCHEMBL9355303 | 0.84 | AKR1C3 (0.57) | AKR1C3RECQLMEN1KMT2AABCG2 | |
| SCHEMBL11417807 | 0.82 | MEN1 (0.66) | AKR1C3MEN1KMT2AALDH1A1 | |
| SCHEMBL28251565 | 0.82 | AKR1C3 (0.43) | AKR1C3RECQLMEN1KMT2AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4194051-A | Asymmetric catalysis | MONSANTO COMPANY (US) | 1980-03-18 | — | — | US | disclosed |