Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | CASP6 | P55212 | 3/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 3/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CD40 | P25942 | 2/20 | 0.42 |
| ▸ | CD40LG | P29965 | 2/20 | 0.42 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.42 |
| ▸ | FGF1 | P05230 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426318 | 0.91 | APEX1 (0.65) | APEX1CASP6CTDSP1ENPP2HDAC1 | |
| SCHEMBL26887682 | 0.90 | APEX1 (0.67) | APEX1CASP6CTDSP1ENPP2HDAC1 | |
| SCHEMBL11440872 | 0.89 | APEX1 (0.63) | APEX1CASP6CTDSP1ENPP2HDAC1 | |
| SCHEMBL13619183 | 0.89 | APEX1 (0.81) | APEX1CASP6CTDSP1ENPP2HDAC1 | |
| SCHEMBL11589917 | 0.89 | APEX1 (0.77) | APEX1CASP6CTDSP1ENPP2HDAC1 | |
| SCHEMBL6560534 | 0.89 | APEX1 (0.77) | APEX1CASP6CTDSP1ENPP2HDAC1 | |
| SCHEMBL10904451 | 0.88 | APEX1 (0.79) | APEX1CASP6CTDSP1ENPP2HDAC1 | |
| SCHEMBL11351805 | 0.87 | APEX1 (0.63) | APEX1CASP6CTDSP1ENPP2NSD2 | |
| SCHEMBL10908350 | 0.87 | APEX1 (0.63) | APEX1CASP6CTDSP1ENPP2NT5E | |
| SCHEMBL26887683 | 0.86 | APEX1 (0.65) | APEX1CASP6CTDSP1ENPP2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |