Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438815 | 0.92 | APEX1 (0.56) | APEX1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11440906 | 0.92 | APEX1 (0.56) | APEX1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11136921 | 0.90 | APEX1 (0.65) | APEX1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11426318 | 0.85 | APEX1 (0.65) | APEX1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11347946 | 0.85 | APEX1 (0.56) | APEX1MAPTTDP1MEN1KMT2A | |
| SCHEMBL10908066 | 0.85 | APEX1 (0.56) | APEX1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11426178 | 0.84 | APEX1 (0.63) | APEX1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11433439 | 0.84 | SMN1; SMN2 (0.57) | APEX1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL11419432 | 0.84 | APEX1 (0.50) | APEX1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11435700 | 0.83 | APEX1 (0.56) | APEX1MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |