Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.65 |
| ▸ | LTA4H | P09960 | 4/20 | 0.65 |
| ▸ | REN | P00797 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | F2 | P00734 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | PEPD | P12955 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | THPO | P40225 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554484 | 0.95 | ACE (0.71) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL11432760 | 0.92 | ACE (0.60) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL10554261 | 0.87 | ACE (0.66) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL11325438 | 0.86 | ACE (0.53) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL10551301 | 0.86 | ACE (0.64) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL7127497 | 0.86 | ACE (0.68) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL11328302 | 0.86 | ACE (0.64) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL11376979 | 0.86 | ACE (0.68) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL11493207 | 0.85 | ACE (0.56) | ACELTA4HRENKDM4EF2 | |
| SCHEMBL7372965 | 0.84 | ACE (0.91) | ACELTA4HRENKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228077-A | N-[2-(mercaptoalkyl)-3-mercaptoalkanoyl]-l-tryptophanes | E. R. SQUIBB & SONS, INC. (US) | 1980-10-14 | — | — | US | disclosed |
| US-4206121-A | ANGIOTENSIN, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1980-06-03 | — | — | US | disclosed |
| US-4178291-A | HYPOTENSIVE AGENTS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-12-11 | — | — | US | disclosed |
| US-4176235-A | ANGIOTENSIN COVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4175199-A | Substituted acyl derivatives of amino acids | E. R. SQUIBB & SONS, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4154936-A | ENZYME INHIBITORS, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4140864-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4116962-A | ANGIOTENSIN CONVERTING ENXYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-26 | — | — | US | disclosed |