Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433644 | 0.89 | MEN1 (0.32) | CYP3A4LMNAGBA1MEN1KMT2A | |
| SCHEMBL11500198 | 0.83 | TDP1 (0.41) | CYP3A4LMNAGBA1SMN1; SMN2MEN1 | |
| SCHEMBL9067517 | 0.82 | CYP3A4 (0.41) | CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL11425775 | 0.78 | KDM4E (0.33) | LMNA | |
| SCHEMBL11425928 | 0.78 | TP53 (0.34) | CYP3A4LMNANOS3NOS1NOS2 | |
| SCHEMBL11440952 | 0.76 | MEN1 (0.33) | LMNANOS3NOS1NOS2GBA1 | |
| SCHEMBL11433898 | 0.74 | TP53 (0.33) | CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL11576507 | 0.73 | TSHR (0.32) | LMNAMEN1KMT2A | |
| SCHEMBL27580960 | 0.72 | TP53 (0.37) | CYP3A4LMNAHPGDMEN1KMT2A | |
| SCHEMBL11428149 | 0.72 | USP2 (0.37) | CYP3A4LMNAHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224050-A | Chloroacetanilides having a selective herbicidal activity, ortho-alkenyl-substituted anilines, intermediates in the synthesis of said herbicidal chloroacetanilides, and methods for their preparation | MONTEDISON S.P.A. (IT) | 1980-09-23 | — | — | US | claimed |