Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.60 |
| ▸ | CYP3A5 | P20815 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437664 | 0.93 | CYP3A4 (0.63) | CYP19A1CYP3A4CYP3A5NPC1RAB9A | |
| SCHEMBL11430409 | 0.86 | CYP3A4 (0.56) | CYP19A1CYP3A4CYP3A5NPC1RAB9A | |
| SCHEMBL11726591 | 0.82 | CYP3A4 (0.50) | CYP19A1CYP3A4CYP3A5NPC1RAB9A | |
| SCHEMBL11726054 | 0.78 | CYP3A4 (0.60) | CYP19A1CYP3A4CYP3A5RORC | |
| SCHEMBL11730843 | 0.78 | CYP3A4 (0.47) | CYP19A1CYP3A4CYP3A5NPC1RAB9A | |
| SCHEMBL11431939 | 0.78 | CYP3A4 (0.57) | CYP3A4CYP3A5NPC1RAB9A | |
| SCHEMBL4473850 | 0.78 | CYP19A1 (0.64) | CYP19A1CYP3A4CYP3A5RAB9ARORC | |
| SCHEMBL9794571 | 0.78 | NPC1 (0.48) | CYP19A1CYP3A4CYP3A5NPC1RAB9A | |
| SCHEMBL11721236 | 0.76 | CYP11B1 (0.46) | CYP19A1CYP3A4CYP3A5NPC1RAB9A | |
| SCHEMBL17171913 | 0.76 | CYP3A4 (0.45) | CYP19A1CYP3A4CYP3A5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4194899-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4110099-A | INHIBITOR FOR INTERNODEL GROWTH OF PLANTS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-RE29367-E | HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4002628-A | HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3967949-A | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |