Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440694 | 0.95 | HDAC1 (0.51) | HSD17B10SMN1; SMN2NPSR1HDAC1KMT2A | |
| SCHEMBL11440774 | 0.92 | HSD17B10 (0.52) | HSD17B10SMN1; SMN2NPSR1HDAC1KMT2A | |
| SCHEMBL17903023 | 0.91 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2NPSR1HDAC1KMT2A | |
| SCHEMBL11758262 | 0.89 | HSD17B10 (0.58) | HSD17B10SMN1; SMN2NPSR1HDAC1KMT2A | |
| SCHEMBL11436491 | 0.88 | HDAC1 (0.46) | HSD17B10SMN1; SMN2HDAC1KMT2ATIMP3 | |
| SCHEMBL11430982 | 0.87 | HSD17B10 (0.52) | HSD17B10SMN1; SMN2NPSR1HDAC1KMT2A | |
| SCHEMBL11427858 | 0.86 | HDAC1 (0.51) | HSD17B10SMN1; SMN2NPSR1HDAC1KMT2A | |
| SCHEMBL11209218 | 0.86 | AURKB (0.53) | HSD17B10SMN1; SMN2NPSR1HDAC1KMT2A | |
| SCHEMBL11341158 | 0.85 | RECQL (0.68) | HSD17B10SMN1; SMN2KMT2ATIMP3RECQL | |
| SCHEMBL10907758 | 0.85 | RECQL (0.59) | HSD17B10SMN1; SMN2KMT2ATIMP3RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |