Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31256869 | 0.95 | MAPT (0.65) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| SCHEMBL3315675 | 0.95 | MAPT (0.65) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| SCHEMBL11410702 | 0.94 | MAPT (0.64) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| Hydrochloric Acid SCHEMBL1785872 | 0.94 | MAPT (0.67) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| Hydrochloric Acid SCHEMBL9818222 | 0.93 | MAPT (0.65) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| Hydrochloric Acid SCHEMBL8414465 | 0.93 | MAPT (0.65) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| Hydrochloric Acid SCHEMBL9497972 | 0.93 | MAPT (0.65) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| Zinc Chloride SCHEMBL29476092 | 0.92 | MAPT (0.65) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| Hydrochloric Acid SCHEMBL8414464 | 0.92 | MAPT (0.64) | MAPTGAAALDH1A1KDM4EHDAC1 | |
| SCHEMBL8004820 | 0.91 | MAPT (0.60) | MAPTGAAALDH1A1KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224027-A | Process for the production of water-insoluble azo dyestuffs on the fiber with polyphosphate | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |