Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | DNA2 | P51530 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31606817 | 0.89 | TDP1 (0.51) | CDK2TDP1TSHRL3MBTL1AKR1C4 | |
| SCHEMBL4442629 | 0.83 | CDK2 (0.48) | CDK2TDP1TSHRL3MBTL1AKR1C4 | |
| SCHEMBL11440938 | 0.81 | TSHR (0.56) | CDK2TDP1TSHRL3MBTL1AKR1C4 | |
| SCHEMBL29405767 | 0.78 | AKR1C4 (0.44) | CDK2TDP1TSHRL3MBTL1AKR1C4 | |
| SCHEMBL30991605 | 0.78 | TSHR (0.56) | CDK2TDP1TSHRL3MBTL1AKR1C4 | |
| SCHEMBL11314439 | 0.78 | TSHR (0.56) | CDK2TDP1TSHRL3MBTL1AKR1C4 | |
| SCHEMBL11808349 | 0.76 | TDP1 (0.55) | CDK2TDP1TSHRL3MBTL1AKR1C4 | |
| SCHEMBL29351965 | 0.75 | TDP1 (0.66) | TDP1TSHRL3MBTL1DNA2CASP6 | |
| SCHEMBL15869336 | 0.75 | TDP1 (0.66) | TDP1TSHRL3MBTL1DNA2CASP6 | |
| SCHEMBL304456 | 0.75 | TDP1 (0.66) | TDP1TSHRL3MBTL1DNA2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212813-A | OXIDIZING ACENAPHTHENES, COBALT COMPOUND CATALYST | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-07-15 | — | — | US | disclosed |