Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441235 | 1.00 | SLC1A2 (0.37) | SLC1A2SLC1A1PEPDMEN1KMT2A | |
| SCHEMBL11441239 | 1.00 | SLC1A2 (0.37) | SLC1A2SLC1A1PEPDMEN1KMT2A | |
| SCHEMBL23481696 | 0.77 | SLC1A2 (0.43) | SLC1A2SLC1A1PEPDMEN1KMT2A | |
| SCHEMBL7063103 | 0.73 | F2 (0.35) | — | |
| SCHEMBL17628741 | 0.71 | ACE (0.44) | SLC1A2SLC1A1PEPDMEN1KMT2A | |
| SCHEMBL10289797 | 0.71 | ACE (0.44) | SLC1A2SLC1A1PEPDMEN1KMT2A | |
| SCHEMBL11447906 | 0.71 | SLC1A2 (0.42) | SLC1A2SLC1A1PEPDMEN1KMT2A | |
| SCHEMBL14072902 | 0.71 | ACE (0.44) | SLC1A2SLC1A1PEPDMEN1KMT2A | |
| SCHEMBL11447904 | 0.71 | SLC1A2 (0.42) | SLC1A2SLC1A1PEPDMEN1KMT2A | |
| SCHEMBL14473782 | 0.71 | ACE (0.44) | SLC1A2SLC1A1PEPDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206137-A | Thioalkanoylalkanoic acid compounds | E. R. SQUIBB & SONS, INC. (US) | 1980-06-03 | — | — | US | disclosed |