Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | ESR1 | P03372 | 2/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | ELANE | P08246 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312147 | 0.97 | KMT2A (0.76) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL9171166 | 0.91 | KMT2A (0.68) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL6282777 | 0.91 | KMT2A (0.68) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL819434 | 0.89 | KMT2A (0.66) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL2239096 | 0.89 | KMT2A (0.66) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7930777 | 0.89 | KMT2A (0.66) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL361899 | 0.89 | KMT2A (0.66) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| Methane SCHEMBL10713166 | 0.87 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL197418 | 0.87 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL9799923 | 0.87 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4192877-A | BIS(POLYALKOXYBENZYL)-TETRAHYDROISOQUINOLIUM ALKYL M- OR P- PHENYLENE DIPROPIONATE SALT | MASSACHUSETTS GENERAL HOSPITAL (US) | 1980-03-11 | — | — | US | disclosed |