Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GRK2 | P25098 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16973505 | 0.88 | KMT2A (0.54) | KMT2AMEN1GAAPOLBGRK2 | |
| SCHEMBL14976630 | 0.88 | KMT2A (0.63) | KMT2AMEN1GAAPOLBL3MBTL1 | |
| SCHEMBL28619310 | 0.85 | GAA (0.66) | KMT2AMEN1GAAPOLBL3MBTL1 | |
| SCHEMBL29463727 | 0.85 | GAA (0.66) | KMT2AMEN1GAAPOLBL3MBTL1 | |
| SCHEMBL11638911 | 0.85 | GAA (0.66) | KMT2AMEN1GAAPOLBL3MBTL1 | |
| SCHEMBL29463748 | 0.85 | GAA (0.66) | KMT2AMEN1GAAPOLBL3MBTL1 | |
| SCHEMBL14975698 | 0.85 | SMN1; SMN2 (0.72) | KMT2AMEN1GAAPOLBSMN1; SMN2 | |
| SCHEMBL9269689 | 0.84 | KMT2A (0.59) | KMT2AMEN1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL14985314 | 0.84 | GAA (0.64) | KMT2AMEN1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL14976546 | 0.82 | GAA (0.62) | KMT2AMEN1GAAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007441-A1 | N - (N-Acetyl-L-methionyl) - 3,4 -diethoxy-carbonyloxy-phenethylamine, process for preparing same and a pharmaceutical composition containing said compound. | Tanabe Seiyaku Co., Ltd. (JP) | 1980-02-06 | — | — | EP | claimed |
| JP-55007242-A | — | — | None | — | — | JP | disclosed |
| CN-101668742-B | Bridged six-membered ring compounds | ACTELION PHARMACEUTICALS LTD | 2014-04-30 | — | — | CN | disclosed |
| CN-101668742-A | Bridged six-membered ring compounds | ACTELION PHARMACEUTICALS LTD | 2010-03-10 | — | — | CN | disclosed |
| US-4228183-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4228183-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| EP-0007441-A1 | N - (N-Acetyl-L-methionyl) - 3,4 -diethoxy-carbonyloxy-phenethylamine, process for preparing same and a pharmaceutical composition containing said compound. | Tanabe Seiyaku Co., Ltd. (JP) | 1980-02-06 | — | — | EP | disclosed |
| EP-0007441-A1 | N - (N-Acetyl-L-methionyl) - 3,4 -diethoxy-carbonyloxy-phenethylamine, process for preparing same and a pharmaceutical composition containing said compound. | Tanabe Seiyaku Co., Ltd. (JP) | 1980-02-06 | — | — | EP | disclosed |
| JP-S557242-A | PHENETHYLAMINE DERIVATIVE | TANABE SEIYAKU CO LTD | 1980-01-19 | — | — | JP | disclosed |