SCHEMBL11447488

SCHEMBL11447488

C=CCC(=O)C1=C(C)CCCC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
HAO1 Q9UJM8 1/20 0.40
RXRA P19793 7/20 0.35
RARB P10826 8/20 0.35
RARG P13631 8/20 0.35
ALDH1A1 P00352 8/20 0.35
RARA P10276 7/20 0.35
MAPT P10636 5/20 0.35
CYP3A4 P08684 5/20 0.35
PTGS1 P23219 4/20 0.35
RXRB P28702 2/20 0.35
RXRG P48443 2/20 0.35
RORC P51449 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
MAPK1 P28482 2/20 0.35
HTR2B P41595 2/20 0.35
BLM P54132 2/20 0.35
HIF1A Q16665 2/20 0.35
APP P05067 2/20 0.35
DRD3 P35462 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17129798 0.80 CYP1A2 (0.44) CYP1A2HAO1RXRARARBRARG
SCHEMBL29496293 0.79 CYP1A2 (0.39) CYP1A2HAO1RXRARARBRARG
SCHEMBL11467133 0.79 HAO1 (0.41) CYP1A2HAO1RXRARARBRARG
SCHEMBL14879901 0.78 CYP1A2 (0.46) CYP1A2HAO1RXRARARBRARG
SCHEMBL11226671 0.77 CYP1A2 (0.41) CYP1A2HAO1RXRARARBRARG
Methane SCHEMBL29372364 0.77 CYP1A2 (0.45) CYP1A2HAO1RXRARARBRARG
SCHEMBL11328784 0.77 HAO1 (0.42) CYP1A2HAO1RXRARARBRARG
SCHEMBL11861435 0.76 HAO1 (0.40) CYP1A2HAO1RXRARARBRARG
SCHEMBL10379604 0.76 MAPT (0.37) MAPTALOX15
SCHEMBL18308880 0.75 CYP1A2 (0.41) CYP1A2HAO1RXRARARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4226892-A Flavoring with cycloaliphatic unsaturated ketones FIRMENICH SA (CH) 1980-10-07 US disclosed
US-4187863-A Cycloaliphatic unsaturated ketones as odor and taste modifying agents in tobacco products FIRMENICH SA (CH) 1980-02-12 US disclosed
US-3975310-A PERFUME FIRMENICH S.A. (CH) 1976-08-17 US disclosed
US-3931326-A FLAVOR, TASTE, ODOR, PERFUMES FIRMENICH SA (CH) 1976-01-06 US disclosed