Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224816 | 0.81 | NAPRT (0.53) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL6319231 | 0.81 | GFER (0.69) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL6320681 | 0.81 | GFER (0.69) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL21572872 | 0.81 | GFER (0.69) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL20525869 | 0.79 | NAPRT (0.52) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL14667494 | 0.79 | NAPRT (0.52) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL5170779 | 0.79 | NAPRT (0.67) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL3415038 | 0.79 | NAPRT (0.67) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL29354342 | 0.78 | GFER (0.68) | GFERNAPRTHSD17B10MAPTGAA | |
| SCHEMBL57554 | 0.78 | SMN1; SMN2 (0.70) | NAPRTHSD17B10MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026894-A1 | Process for the preparation of erythro-alpha-2-piperidyl-2,8-bis (trifluoromethyl)-4-quinoline methanol | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |