Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665744 | 0.84 | SSTR4 (0.40) | SSTR4MAOBCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11285190 | 0.81 | HDAC3 (0.42) | SSTR4CYP2D6CYP2C19 | |
| SCHEMBL13301356 | 0.78 | CYP1A2 (0.44) | SSTR4MAOBCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25144902 | 0.76 | CYP1A2 (0.43) | SSTR4MAOBCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2341418 | 0.76 | MEN1 (0.42) | MAOB | |
| SCHEMBL11661682 | 0.75 | SSTR4 (0.39) | SSTR4MAOBCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5048630 | 0.75 | AR (0.47) | SSTR4MAOBAR | |
| SCHEMBL12392883 | 0.75 | MAOB (0.47) | SSTR4MAOBAR | |
| SCHEMBL12392895 | 0.75 | MAOB (0.47) | SSTR4MAOBAR | |
| SCHEMBL7877126 | 0.75 | MAOB (0.44) | SSTR4MAOBCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210651-A | Thiaprostaglandins | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-07-01 | — | — | US | disclosed |
| US-4080458-A | HYPOTENSIVE AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-03-21 | — | — | US | disclosed |