SCHEMBL11455191

SCHEMBL11455191

O=C1N=c2ccc3c(c2NC1=O)C=CN=3

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8350441 0.75
SCHEMBL29732 0.73
Hydrochloric Acid SCHEMBL9090799 0.73
Hydrochloric Acid SCHEMBL28632568 0.72
SCHEMBL332957 0.72
SCHEMBL16913025 0.72
SCHEMBL2681012 0.72
Water SCHEMBL30891750 0.71
Glycerin SCHEMBL17353367 0.65
SCHEMBL4146411 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE30415-E ANTIINFLAMMATORY AGENTS, ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1980-10-07 US disclosed
US-RE30314-E ANTIINFLAMMATORY, ANTITHROMBOTIC ELI LILLY AND COMPANY (US) 1980-06-24 US disclosed
US-4133884-A Substituted pyrroloquinoxalinones and diones used in treating inflammation in warm blooded mammals ELI LILLY AND COMPANY (US) 1979-01-09 US disclosed
US-4087527-A ANTIINFLAMMATORY AND ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed
US-4075206-A ANTIINFLAMMATORY, ANTITHROMBOTIC ELI LILLY AND COMPANY (US) 1978-02-21 US disclosed