Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 13/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.58 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.58 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 11/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085618 | 0.82 | TAAR1 (0.55) | CARM1PRMT6PRMT8PRMT3TAAR1 | |
| SCHEMBL15308529 | 0.82 | MAPT (0.50) | TAAR1KDM4EMAPTCHRM2 | |
| SCHEMBL11638292 | 0.82 | MEN1 (0.55) | TAAR1KDM4EMAPTCHRM2 | |
| SCHEMBL13975072 | 0.79 | CHRM2 (0.47) | KDM4EMAPTCHRM2 | |
| SCHEMBL18917918 | 0.79 | CARM1 (0.69) | CARM1PRMT6PRMT8PRMT3TAAR1 | |
| SCHEMBL13965855 | 0.78 | KDM4E (0.46) | TAAR1PRMT1KDM4EMAPTCHRM2 | |
| SCHEMBL19074373 | 0.78 | CHRM2 (0.50) | KDM4EMAPTCHRM2 | |
| SCHEMBL14948896 | 0.78 | CHRM2 (0.46) | KDM4EMAPTCHRM2 | |
| SCHEMBL12124982 | 0.78 | MAPT (0.53) | TAAR1KDM4EMAPT | |
| SCHEMBL2119569 | 0.77 | CARM1 (0.53) | CARM1PRMT6PRMT8PRMT3PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197243-A | ANTIPSYCHOTICS, STRONG CNS DEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |
| US-4097487-A | CNS DEPRESSANTS, ANTIPSYCHOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1978-06-27 | — | — | US | disclosed |