Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 6/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | C1R | P00736 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439560 | 0.82 | C5AR1 (0.71) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL11449738 | 0.79 | C5AR1 (0.67) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL7150548 | 0.79 | C5AR1 (0.83) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL9498051 | 0.78 | C5AR1 (0.60) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL24125226 | 0.76 | C5AR1 (0.77) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL3257725 | 0.76 | C5AR1 (0.77) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL942802 | 0.76 | C5AR1 (0.77) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL944589 | 0.75 | C5AR1 (0.75) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL11441279 | 0.74 | C5AR1 (0.67) | C5AR1CA12CA9LMNATSHR | |
| SCHEMBL25920653 | 0.73 | C5AR1 (0.62) | C5AR1CA12CA9LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4237127-A | MITICIDES, LARVICIDES, OVICIDES | FISONS LIMITED (GB) | 1980-12-02 | — | — | US | disclosed |
| US-4183955-A | Troponyl-oxamic acid derivatives for treating allergic conditions | Ayerst. McKenna & Harrison Limited (CA) | 1980-01-15 | — | — | US | disclosed |
| US-4125625-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-11-14 | — | — | US | disclosed |
| US-4057556-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1977-11-08 | — | — | US | disclosed |