Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.64 |
| ▸ | CNR1 | P21554 | 11/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18671 | 0.94 | ESR1 (0.60) | CNR2CNR1ESR1ESR2SHBG | |
| SCHEMBL3445177 | 0.93 | CNR2 (0.58) | CNR2CNR1ESR1ESR2SHBG | |
| SCHEMBL678357 | 0.93 | CNR2 (0.58) | CNR2CNR1ESR1ESR2SHBG | |
| SCHEMBL3720371 | 0.93 | CNR2 (0.58) | CNR2CNR1ESR1ESR2SHBG | |
| SCHEMBL27813196 | 0.93 | CNR2 (0.58) | CNR2CNR1ESR1ESR2SHBG | |
| SCHEMBL10890723 | 0.93 | CNR2 (0.58) | CNR2CNR1ESR1ESR2SHBG | |
| SCHEMBL20500878 | 0.93 | CNR2 (0.58) | CNR2CNR1ESR1ESR2SHBG | |
| SCHEMBL5613165 | 0.91 | CNR2 (0.74) | CNR2CNR1 | |
| Formaldehyde SCHEMBL290372 | 0.89 | ESR1 (0.55) | CNR2CNR1ESR1ESR2SHBG | |
| SCHEMBL199439 | 0.89 | ESR1 (0.68) | CNR2CNR1ESR1ESR2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230867-A | REDUCTION, CYCLIZATION OF NITROAZOBENZENES | CIBA-GEIGY CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4219480-A | REDUCTION OF UNDESIRED BY-PRODUCT AND EFFLUENT POLLUTION PROBLEMS | CIBA-GEIGY CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4141903-A | REDUCTION AND CYCLIZATION OF THE CORRESPONDING O-NITROAZOBENZENES WITH CARBON MONOXIDE USING A COPPER-AMINE COMPLEX AS CATALYST | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4041044-A | BY REDUCTION OF CORRESPONDING O-NITRO-AZOBENZENES WITH ZINC IN AQUEOUS ALKALI METAL HYDROXIDE | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |