Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684742 | 0.82 | MAPT (0.37) | TSHRLMNAALDH1A1TDP1ACHE | |
| SCHEMBL9577875 | 0.76 | HTR2C (0.41) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL16824941 | 0.76 | KDM1A (0.55) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL11684978 | 0.75 | HTR2A (0.41) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL14253687 | 0.70 | KDM1A (0.53) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL20916724 | 0.69 | KDM1A (0.55) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL11455590 | 0.69 | KDM1A (0.51) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL8848929 | 0.68 | PDK2 (0.40) | ALDH1A1ACHEHSP90AA1KMT2AMEN1 | |
| SCHEMBL9558059 | 0.68 | CYP1A2 (0.45) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL10184986 | 0.67 | TSHR (0.57) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3930835-A | PESTICIDAL COMPOSITIONS AND METHODS EMPLOYING SUBSTITUTED OXIRANE COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | claimed |
| US-4211549-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| US-4018801-A | PESTICIDES | THE DOW CHEMICAL COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4013772-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3930835-A | PESTICIDAL COMPOSITIONS AND METHODS EMPLOYING SUBSTITUTED OXIRANE COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | disclosed |